Singapore's IBN and NUH to test cutting-edge materials to treat eye diseases

World's first photochromic contact lens that darken with sunlight exposure among Institute of Bioengineering and Nanotechnology advances

Marking a significant bench to bedside research milestone in Singapore, the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute, and the National University Hospital (NUH) launched the IBN iCare and the NUH Eye Centre @ Biopolis at an official opening ceremony officiated by the Senior Minister of State for Trade and Industry and Education, S. Iswaran, at the Biopolis on Nov. 3, 2009.

Collaborations between researchers and clinicians are critical to speed up the translation of basic scientific discoveries into clinical applications, and develop new medical products and treatments. IBN iCare is the first research laboratory in Singapore to focus on the development of cutting-edge nanomaterials for ocular therapy.

The NUH Eye Centre @ Biopolis will provide a clinical research environment that facilitates the development of new materials and techniques for ophthalmology practice. IBN's nanostructured ocular materials will undergo clinical trials at the NUH Eye Centre prior to commercial applications.

Since 2003, IBN has been revolutionizing medical treatment with sophisticated biomaterials and systems for delivering therapeutics to diseased cells and organs. This key research thrust at IBN has led to the synthesis of a novel drug-loaded contact lens that can deliver medication more effectively than eye drops for the treatment of eye diseases such as glaucoma. The latest ocular research invention created by IBN is the world's first photochromic contact lens that will darken upon exposure to sunlight to protect the eyes against harmful ultraviolet radiation and glare. The lenses will conveniently adapt to changes in light and provide optimal indoor and outdoor vision.

"IBN's mission is to conduct strategic research that addresses important biomedical problems through novel technology platforms that present major commercial potential. The launch of IBN iCare and our collaboration with NUH symbolize our commitment towards establishing Singapore as an international, world class biomedical hub. By bridging the gap from bench to bedside, we are well positioned to facilitate the commercialization of our research innovations," said Professor Jackie Y. Ying, IBN Founding Executive Director.

Recognizing the commercial potential of IBN's ocular biomaterials, Exploit Technologies Pte Ltd (ETPL), the strategic marketing and commercialization arm of the Agency for Science, Technology and Research (A*STAR), provided a S$5 million Flagship Fund to set up IBN iCare. IBN iCare will accelerate the translation of strategic research in vision care to viable medical products and treatments. Its mission is to incubate start-up companies in vision care, and attract more global partners to Singapore to create a major commercial impact on myopia and vision impairment treatment.