NYU dental professor discovers biological clock linking tooth growth to other metabolic processes

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Reporting his findings today in the “Late-breaking News” session during the 37th Annual Meeting of the American Association for Dental Research, Bromage said, “The same biological rhythm that controls incremental tooth and bone growth also affects bone and body size and many metabolic processes, including heart and respiration rates. In fact, the rhythm affects an organism’s overall pace of life, and its life span. So, a rat that grows teeth and bone in one-eighth the time of a human also lives faster and dies younger.”

Humans have by far the most variation in these long-term incremental growth rhythms, with some humans clocking as few as five days, and others as many as ten. Correspondingly, humans have the most variability in body size among mammals.

Future research will assess whether there is a link between slower growth rhythms and growth disorders. Since the autonomic nervous system controls human behavior, future research will also assess whether growth rhythms can be linked to variations in human behavior.

Dr. Bromage is an Adjunct Professor of Basic Science and Craniofacial Biology and of Biomaterials and Biomimetics at the NYU College of Dentistry.

Founded in 1865, New York University College of Dentistry is the third oldest and the largest dental school in the United States, educating more than 8 percent of all dentists. NYUCD has a significant global reach and provides a level of national and international diversity among its students that is unmatched by any other dental school. In 2005, the NYU Division of Nursing became a College of Nursing located within the NYU College of Dentistry.