JCI table of contents: Nov. 1, 2007

In the second study, Edward Weinman and colleagues from the University of Maryland School of Medicine, Baltimore, showed that in murine and primate kidney cells, Na+-dependent phosphate transporter (Npt2a) was regulated by phosphorylation of serine 77 (S77) of the Npt2a-binding protein sodium-hydrogen exchanger regulatory factor-1 (NHERF-1). Such phosphorylation inhibited phosphate transport in the kidney and was shown to be the mechanism by which the hormone PTH inhibits kidney reabsorption of phosphate.

TITLE: The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex

AUTHOR CONTACT:
David H. Ellison
Oregon Health & Science University, Portland, Oregon, USA.
Phone: (503) 494-8490; Fax: (503) 494-5330; E-mail: .

Chao-Ling Yang
Oregon Health & Science University, Portland, Oregon, USA.
Phone: (503) 494-8490; Fax: (503) 494-5330; E-mail:

MEDIA CONTACT:
Harry Lenhart
Senior Communications Coordinator
Oregon Health & Science University, Portland, Oregon, USA.
Phone: (503) 494-1360; Fax: (503) 494-8246; E-mail: .

View the PDF of this article at: https://www.the-jci.org/article.php?id=32033

RELATED MANUSCRIPT

TITLE: Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor–1

AUTHOR CONTACT:
Edward J. Weinman
University of Maryland School of Medicine, Baltimore, Maryland, USA.
Phone: (410) 706-1555; Fax: (410) 706-4195; E-mail: .

View the PDF of this article at: https://www.the-jci.org/article.php?id=32738

ACCOMPANYING COMMENTARY

TITLE: Kidney kinase network regulates renal ion cotransport

AUTHOR CONTACT:
Juerg Biber
University of Zurich, Zurich, Switzerland.
Phone: 41-044-635-5032; Fax: 41-044-635-5715; Email: .

View the PDF of this article at: https://www.the-jci.org/article.php?id=33859