Integrated optical trap holds particles for on-chip analysis

Optical traps and "optical tweezers" use the momentum carried by the photons in a beam of light to exert forces on microscopic objects, enabling researchers to manipulate objects ranging from biological molecules to living cells. Schmidt's group developed a new way to perform optical trapping on a chip-based platform.

The technique relies on an earlier innovation from Schmidt's lab: a hollow-core optical waveguide that can direct a beam of light through a liquid-filled channel on a chip. To trap particles, the researchers used two laser beams at opposite ends of a channel. A particle gets trapped at the point where the forces exerted by the two beams are equal, and the particle can be moved by changing the relative power of the two laser beams.

"We can also use this like an optical leaf blower to push all the particles in a sample to the same spot and increase the concentration," Schmidt said. "The goal is to control the position and movement of particles through channels on a chip so they can be studied using fluorescence analysis and other optical methods."

The Jack Baskin School of Engineering at UCSC prepares technologists--and sponsors technology--for our changing world. Founded in 1997, Baskin Engineering trains students in six future-focused areas of engineering: biotechnology/information technology/ nanotechnology; information and communication infrastructure; mathematical and statistical modeling; software and services engineering; system design; and bioengineering. Baskin Engineering faculty conduct industry-leading research that is improving the way the world does business, treats the environment, and nurtures humanity.